KLOW

KLOW Blend – GHK-Cu (50 mg) · BPC-157 (10 mg) · TB-500 (10 mg) · KPV (10 mg)

KLOW is a multi-pathway regenerative research blend combining GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex), BPC-157 (Body Protection Compound-157), TB-500 (Thymosin Beta-4 fragment), and KPV, a bioactive tripeptide derived from α-melanocyte-stimulating hormone. This formulation integrates extracellular matrix remodeling, angiogenesis, cytoskeletal repair, epithelial barrier stabilization, and targeted anti-inflammatory signaling to support coordinated tissue regeneration.

In preclinical and experimental models, KLOW has been associated with accelerated wound healing, enhanced skin and connective tissue repair, improved hair follicle and scalp health, suppression of pro-inflammatory cytokines, and protection against oxidative and inflammation-driven cellular damage. Its combined regenerative and inflammation-modulating profile makes KLOW a compound of interest in dermatological, cosmetic, gastrointestinal, and regenerative biology research.

$179.99

In stock

Disclaimer: This compound is not intended for human or veterinary use. KLOW is sold strictly for laboratory research purposes only. Any mention of effects is provided for educational information and relates solely to preclinical or experimental studies and does not imply efficacy in humans.

KLOW Summary

KLOW Blend – GHK-Cu (50 mg) · BPC-157 (10 mg) · TB-500 (10 mg) · KPV (10 mg)

Advanced Tissue Regeneration & Accelerated Wound Healing

GHK-Cu stimulates collagen, elastin, and glycosaminoglycan synthesis to restore extracellular matrix (ECM) architecture.
BPC-157 enhances angiogenesis, fibroblast migration, and epithelial repair across soft tissue and connective tissue injury models.
TB-500 promotes actin polymerization and cellular motility, enabling rapid cell migration into damaged tissue.
KPV supports epithelial integrity and suppresses inflammatory disruption at wound sites, creating a pro-healing microenvironment.
The combined formulation accelerates wound closure, improves tissue tensile strength, and supports organized regeneration across skin, muscle, tendon, ligament, gastrointestinal, and corneal injury models.

Skin Rejuvenation & Barrier Repair Research

GHK-Cu improves skin thickness, elasticity, firmness, and dermal structure in photoaged and mature skin models.
KPV reinforces epidermal barrier function and reduces inflammatory skin responses, particularly in irritation and inflammatory skin models.
BPC-157 stabilizes dermal microvasculature and promotes repair following mechanical or inflammatory damage.
TB-500 enhances cytoskeletal remodeling and cellular turnover for smoother, more uniform skin architecture.
Demonstrates reductions in fine lines, uneven texture, erythema, and barrier dysfunction in cosmetic and dermatologic research.

Hair Growth & Follicular Regeneration

GHK-Cu expands follicle size, prolongs the anagen phase, and activates dermal papilla cell signaling.
BPC-157 improves scalp microcirculation and follicular repair following inflammatory stress.
TB-500 supports stem cell migration and follicle regeneration signaling pathways.
KPV reduces perifollicular inflammation, supporting a healthier scalp environment conducive to hair growth.
Associated with improved hair density, follicle integrity, and growth-phase maintenance in preclinical alopecia models.

Inflammation Modulation & Immune Homeostasis

KPV directly suppresses pro-inflammatory cytokines including TNF-α, IL-1β, IL-6, and downstream inflammatory cascades.
GHK-Cu inhibits NF-κB and p38 MAPK signaling pathways involved in chronic inflammation.
BPC-157 stabilizes endothelial and epithelial barriers, reducing immune cell infiltration and edema.
TB-500 promotes resolution-phase macrophage activity rather than prolonged inflammatory signaling.
Supports controlled, regeneration-supportive inflammation across skin, gut, lung, and connective tissues.

Antioxidant Defense & Cellular Protection

GHK-Cu scavenges reactive oxygen species (ROS) and increases expression of antioxidant enzymes such as superoxide dismutase.
Chelates pro-oxidant metals, limiting lipid peroxidation and oxidative tissue damage.
BPC-157 protects mitochondrial integrity and reduces oxidative stress in muscle and connective tissue models.
KPV reduces inflammation-induced oxidative injury, particularly in epithelial tissues.
Provides cellular and DNA protection against UV exposure, environmental stressors, and inflammatory oxidative damage.

Gene Expression & Regenerative Signaling

GHK-Cu modulates expression of over 30% of human genes associated with repair, inflammation control, and aging.
Upregulates genes involved in collagen synthesis, angiogenesis, antioxidant defense, and stem cell activation.
Downregulates matrix-degrading enzymes (MMPs) and pro-aging inflammatory pathways.
TB-500 and BPC-157 enhance intracellular signaling and tissue-level communication supporting regeneration.
KPV biases gene expression toward anti-inflammatory and barrier-protective phenotypes.
Collectively reprograms fibroblasts and epithelial cells toward a youthful, repair-oriented state

Connective Tissue, Joint & Gastrointestinal Support

BPC-157 supports tendon-to-bone healing, ligament repair, and gastrointestinal mucosal regeneration.
TB-500 assists muscle fiber repair and cytoskeletal remodeling essential for connective tissue recovery.
GHK-Cu enhances proteoglycan and collagen synthesis in cartilage and joint surface models.
KPV supports intestinal barrier integrity and reduces inflammatory signaling in gut tissue models.
Demonstrates relevance for experimental models of connective tissue degeneration, joint aging, and inflammatory gut conditions.

Anti-Fibrotic Activity & Scar Optimization

GHK-Cu inhibits excessive myofibroblast activation and abnormal collagen accumulation.
BPC-157 promotes balanced ECM remodeling and reduces fibrotic tissue formation.
TB-500 encourages organized tissue regeneration over dense scar development.
KPV limits inflammation-driven fibrosis by suppressing cytokine overactivation.
Supports regeneration-dominant healing with minimized scarring in skin, cardiac, and connective tissue models.

Summary
KLOW is an advanced anti-inflammatory–regenerative research blend designed to integrate tissue repair, skin and barrier rejuvenation, immune modulation, hair follicle support, and connective tissue regeneration, with added emphasis on inflammation suppression and epithelial protection via KPV.

This multi-pathway profile makes KLOW particularly relevant for dermatologic, gastrointestinal, cosmetic, and regenerative biology research applications.