Top 5 Peptides for Immune Support Research
Introduction
The immune system is vital for defending the body against pathogens and maintaining overall health. In research settings, several peptides are being extensively studied for their ability to modulate immune responses, enhance antiviral defenses, and balance inflammation.
This guide explores the top 5 peptides researchers are focusing on for immune system studies. Lets explore Immune Support research.
Disclaimer: All peptides discussed are intended for laboratory research use only and are not approved for human consumption.
1. Thymosin Alpha-1 (Tα1)
Thymosin Alpha-1 is one of the most extensively studied peptides for immune enhancement. It stimulates T-cell production, promotes dendritic cell activation, and helps balance pro- and anti-inflammatory cytokines.
Key Research Highlights:
- Boosts antiviral immunity (HBV, HCV, HIV)
- Supports cancer immunotherapy
- Reduces inflammatory damage in sepsis and viral models
2. LL-37
LL-37 is a cationic antimicrobial peptide that not only destroys pathogens directly but also modulates the immune response. It bridges innate and adaptive immunity by influencing cytokine profiles.
Key Research Highlights:
- Inhibits bacterial and viral replication
- Promotes epithelial barrier protection
- Modulates IL-6, TNF-α, and IL-10 expression
3. Glutathione
While not a peptide per se, Glutathione is a crucial antioxidant involved in immune cell function. Maintaining optimal glutathione levels enhances T-cell responses and reduces oxidative stress-driven inflammation.
Key Research Highlights:
- Supports macrophage and NK cell function
- Regulates redox-sensitive cytokine signaling
- Protects lymphocytes during oxidative stress
4. Selank
Selank, known primarily for its anxiolytic effects, has demonstrated immune-modulatory properties. It balances Th1/Th2 cytokines and may enhance antiviral defense mechanisms.
Key Research Highlights:
- Modulates IL-6 and IFN-γ levels
- Enhances resistance to stress-induced immune decline
- Supports vaccine immunogenicity in models
5. NAD⁺
NAD⁺ plays an essential role in immune cell metabolism. Declines in NAD⁺ levels impair immune function, making it a focus in aging and infection research.
Key Research Highlights:
- Enhances mitochondrial function in immune cells
- Activates sirtuins that regulate inflammation
- Supports T-cell energy requirements
Summary Table
| Peptide | Key Immune Functions |
|---|---|
| Thymosin Alpha-1 | T-cell activation, antiviral immunity |
| LL-37 | Antimicrobial action, inflammation control |
| Glutathione | Redox regulation, lymphocyte protection |
| Selank | Cytokine modulation, stress immunity |
| NAD⁺ | Immune metabolism and sirtuin activation |
Final Thoughts
Peptides and peptide-like molecules provide researchers with powerful tools to modulate, restore, and protect immune function in experimental models.
At ReviveLab, we offer high-purity peptides for non-human laboratory research, compliant with Health Canada research-use-only standards.
All compounds are for laboratory use only. Not for human consumption.